What is the dosing guideline for Activated Charcoal in adults?

The dosing guideline for Activated Charcoal in adults is typically 1 gram per kilogram of body weight. This dosage is effective in adsorbing various toxins and drugs in the gastrointestinal tract, thereby reducing their absorption into the bloodstream and mitigating potential toxic effects after an overdose or poisoning. The rationale for using activated charcoal at this dosing level is based on clinical studies which suggest that it promotes optimal binding with a wide range of substances, maximizing its efficacy in decontaminating the gastrointestinal tract.

Other options, such as 50mg/kg or 10mg/kg, do not align with established protocols and may not provide adequate gastrointestinal decontamination, while the 0.5gm/kg option would be insufficient for effective treatment, potentially compromising patient safety. Therefore, the guideline of 1gm/kg represents a balance between safety and efficacy in the treatment of poisonings in adults.