What class of medication is Diltiazem (Cardizem)?

Diltiazem, commonly known by its brand name Cardizem, belongs to the class of medications known as calcium channel blockers. These drugs work by inhibiting the influx of calcium ions into cardiac and smooth muscle cells through voltage-gated calcium channels. This mechanism leads to a decrease in the force of contraction of the heart (negative inotropic effect), as well as a relaxant effect on vascular smooth muscle, which results in vasodilation.

By promoting relaxation of the arterial walls, calcium channel blockers like Diltiazem help to lower blood pressure and can be effective in treating conditions such as hypertension and angina. Additionally, Diltiazem is used in the management of certain types of arrhythmias due to its effects on the conduction system of the heart. Its ability to decrease heart rate and control atrial fibrillation makes it particularly useful in those clinical contexts.

Understanding the pharmacological effects of Diltiazem as a calcium channel blocker is crucial for paramedics and healthcare providers, as it allows for proper patient management and treatment decisions during emergencies related to cardiovascular conditions.